Schaeffer's Top Stock Picks for '25

Biotech Stocks Ripe for a Short Squeeze

There’s a great deal of risk to biotech stocks that aren’t blue chips

Managing Editor
Jun 23, 2023 at 8:49 AM
facebook X logo linkedin


Subscribers to Chart of the Week received this commentary on Sunday, June 18.

The biotech sector comes with a large ‘buyer beware’ sticker. Most stocks in the sector are prone to volatile moves depending on the efficacy of their drug pipeline that in and of itself depends on Food and Drug Administration (FDA) approval. Reading biotech tea leaves can be boiled down to dart throws at knowledge that’s esoteric to even the most seasoned investor. But what if there was a way to cut through the noise, and at the very least, identify common contrarian threads with biotech stocks?

The SPDR S&P Biotech ETF (XBI) was identified last week for its June seasonality that so far, thanks to a 5.6% gain for the month, is ringing true. The fund’s top three holdings are ImmunoGen (IMGN), Viking Therapeutics (VKTX), and TG Therapeutics (TGTX). These three stocks – and a few others -- are all ripe for a short squeeze that could continue to catch bearish bettors leery of biotech volatility off guard.

Schaeffer’s Senior Quantitative Analyst Rocky White compiled a table of stocks where the shorts might be at a big loss and therefore likely to begin covering. It consists of names where short interest has increased by at least 25% since it’s low over the past year, ranked by stocks for which the shorts are at the biggest loss (at least 10%). One caveat, per White: “Obviously, there are quite a few assumptions, so these would be very rough estimates. To estimate the return for the shorts I went back over the past year of short interest reports to find when the shorts were added. Then I used the average price over the prior two weeks and estimated the shorts were added at that average price. I use a weighted average by increase in shares short to find the average price the shorts are in at. Then I calculate the return the shorts are at.”

You can see that the squeeze could already be in for IMGN, with a slim 3.6% of its total available float now sold short, down roughly 50% from 7%. ImmunoGen stock is up 259% year-to-date, one of the biggest winners of 2023 so far. VKTX is 152% higher year-to-date, with chart support at its 40-day moving average in place and a healthy 11% of its total available float sold short.

89bio (ETNB) may not be a top holding of XBI, but at the stock’s average pace of trading, it would take shorts five trading days to buy back their bearish bets. ETNB has tacked on 66% in 2023 and 521% year-over-year. It’s a similar story with TGTX; up 121% year-over-year, chart support at the 50-day trendline, and yet 8.8% of its total available float sold short. Another name from the table to monitor is Axsome Therapeutics Inc (AXSM), with 18.5% of the stock’s total available float sold short.

As a reminder, there’s still a great deal of risk to biotech stocks that aren’t blue chips like Merck (MRK) or Amgen (AMGN). And the names above are all outperforming at such a rate that there could be a ‘FOMO’ rush, by taking a flier on them now. Thus, in lieu of tying up cash with share purchases (or accepting the steep risk profile and margin requirements of selling shares short), one can reduce cash outlay and overall market exposure through the purchase of options, while still participating in a stock's directional movement. All these biotech stocks boast attractively priced options, with IMGN, VKTX, ETNB, TGTX, and AXSM boasting SVI’s all that rank in below the 10th percentile of their respective annual ranges.

shortinterestchartcotw

 
 

Which of These SUB-$5 Stocks Could 26x From Here? (AD)

He called a rare 11x on Tesla…

Then he called a 26x on Workhorse…

Then an even rarer 35x on Nio Inc…

Now Tim Bohen says these 5 tiny “America First” stocks are next up in 2025.

They’re trading for less than $5 right now.

But thanks to Elon & Trump’s new alliance…

They could be off to the races in Trump’s first 100 days.

And right now for a limited time…

You can get the names & tickers for just $1 here. (AD)

10 Stock Picks FREE
 
 

Featured Articles from Trusted Partners:

🚀 One Stock Pick Could Change Everything in 2025
What if one stock pick could define your success next year? Get 10 expert-vetted stocks set for 2025—plus 5 bonus picks to watch now. Get the Report →

🆕 New Options Need New Trading Strategies
Zero-DTE options are the newest (and hottest) options to trade.  Professional traders have rushed into the market and are making a mint.  Don’t get left behind - learn all about these options, how to trade them, market setups to profit from, plus much more. Download now →

👀 Revealed: 3 Defensive Stocks for Your Portfolio
Worried about the market? This free report reveals 3 under-the-radar defensive stocks for uncertain times in any kind of economy.

 

 
 

FREE Report Download

 

Follow us on X, Follow us on Twitter