Schaeffer's Top Stock Picks for '25

3 Biotechs Breaking Out Big

Drugmakers Calithera Biosciences Inc (NASDAQ:CALA), Evoke Pharma Inc (NASDAQ:EVOK), and Pacific Biosciences of California (NASDAQ:PACB) are on fire today

Oct 7, 2015 at 2:59 PM
facebook X logo linkedin


It's been an up-and-down day for the broader market, yet the biotech sector has been charting a path steadily higher. Among the outperforming stocks are Calithera Biosciences Inc (NASDAQ:CALA), Evoke Pharma Inc (NASDAQ:EVOK), and Pacific Biosciences of California (NASDAQ:PACB). Here's a closer look at this trio of equities, as well as Wall Street's expectations.

CALA has popped almost 3% this afternoon to trade at $7.30. This represents a change of pace for a stock that's plummeted 78% since touching a mid-December record peak of $33.48.

Short sellers have been piling on amid this long-term swoon. In fact, nearly 47% of CALA's float is dedicated to short interest, representing 13 days' worth of activity, at typical trading volumes. Conversely, all three analysts tracking the shares rate them a "strong buy." Should CALA resume its withstanding trend south, a round of downgrades could ensue.

EVOK was last seen 23.6% higher at $4.08, lifted by the company's projection that its current cash resources can likely support operations for the next year. Separately, Noble Financial initiated coverage on the stock with a "buy" rating, providing another upward catalyst.

The bullish brokerage attention is par for the course. Heading into today, 100% of analysts considered EVOK worthy of a "strong buy" endorsement. Short sellers are less convinced -- as evidenced by the fact short interest nearly tripled during the last two reporting periods.

Looking at the charts, short sellers may have a point. Even after today's huge gains, EVOK is 31% lower on the year, and has seen recent spikes -- including the current one -- contained by its descending 80-day moving average.

Last but not least, Illumina, Inc. (NASDAQ:ILMN) rival PACB has jumped over 20% to hover near $7.65 -- bringing it within striking distance of its year-to-date flatline. The surge has intraday option volume running at five times the typical clip -- led by the now in-the-money November 7.50 call.

With PACB tentatively scheduled to report earnings within the next couple weeks, option bulls may be rolling the dice on post-earnings gains. Historically speaking, though, the shares have tended to fall in the session subsequent to the reports -- posting negative returns in five of the past eight quarters. With 28% of PACB's float sold short, it's also possible call buyers may be short sellers hedging against extended upward momentum. 
 
 

You have the chance to join one of Bernie's most exclusive programs, complete access at HUGE savings!

As we prepare for a new administration to take the reins in Washington, the near-term market landscape is rife with uncertainty.

The Federal Reserve has already hinted at the turbulence ahead, lowering its interest rate outlook for 2025.

Meanwhile, breakthroughs in artificial intelligence (AI), quantum computing, and other transformative sectors have unlocked incredible profit potential.

But these opportunities are fleeting, and timing is everything. That's where Quick-Hit Trader comes in.

Quick-Hit Trader is designed for precision and speed, getting you in and out of the market in a flash. While other investors scramble to navigate volatile conditions, you'll have access to expertly curated trades that leverage these rapid shifts to deliver explosive profits in short order.

This is your chance to capitalize on the fast-moving market like never before. Are you ready to make your move?